A daily adaptogen formulation designed to support stress modulation, mood stability, and sleep quality during menopause and perimenopause. Combines clinically studied Ashwagandha with black pepper to optimize bioavailability.

All batch testing and Certificates of Analysis are available in the Menopause Science Trust Center.

Clinical Profile

Targets

• Stress response and cortisol regulation

• Mood variability

• Sleep latency and continuity

• Nervous system support during hormonal transition

Primary Active

Organic Ashwagandha Root (Withania somnifera) — 1000 mg per serving
An adaptogenic herb shown to support stress resilience, mood stability, and sleep regulation.

Formulation Rationale

Hormonal changes and stress can disrupt mood regulation and sleep patterns. This formulation combines Ashwagandha with black pepper to enhance absorption and maximize physiological impact.

Organic Black Pepper (Piper nigrum) — Increases bioavailability of active constituents in Ashwagandha.

The formulation is designed for daily use to support multiple pathways involved in stress response, mood regulation, and sleep quality without sedation

Key Characteristics

• Clinically aligned Ashwagandha dosage

• Black pepper–enhanced absorption

• Vegan, non-GMO, gluten-free, sugar-free

• Free from artificial fillers and preservatives

• Manufactured in a GMP-certified, FDA-registered facility

Full Ingredient List

Organic Ashwagandha Root
Organic Black Pepper
Vegetable Capsule

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Trust Center Verified

Comprehensive analysis of clinical research and evidence*

Mood & Sleep Support By Menopause Science

Clinical research shows that up to 80% of perimenopausal women experience mood disturbances and sleep problems. Mood and Sleep Support provides organic ashwagandha root enhanced with black pepper extract for maximum bioavailability and effectiveness.*

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Research Summary

Clinical research suggests that ashwagandha supplementation may significantly reduce perceived stress, anxiety, and improve sleep quality while supporting healthy cortisol levels. Studies specifically in perimenopausal women suggest that ashwagandha may reduce total menopause symptom scores, with particular benefits for psychological symptoms, mood disturbances, and sleep disruption. The addition of black pepper extract (piperine) may enhance absorption, potentially ensuring optimal therapeutic benefits.*

Research at a Glance

Plain Language Summary

Ashwagandha has been studied in adults, including women going through perimenopause, for its potential role in reducing stress, supporting mood, and improving sleep. Several clinical trials suggest it may help lower perceived anxiety, support healthier cortisol levels, and improve sleep quality. When combined with black pepper extract, absorption may be enhanced, which could increase effectiveness.*

Key Citations

Primary Research in Perimenopausal Women:

1. Gopal S, et al. Effect of an ashwagandha (Withania Somnifera) root extract on climacteric symptoms in women during perimenopause: A randomized, double-blind, placebo-controlled study. J Obstet Gynaecol Res. 2021;47(12):4414-4425. PubMed: 34553463

Supporting Stress and Anxiety Research:

1. Chandrasekhar K, et al. A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults. Indian J Psychol Med. 2012;34(3):255-262. PubMed: 23439798

2. Lopresti AL, et al. An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract. Medicine. 2019;98(37):e17186. Medicine Journal

Sleep Research:

1. Cheah KL, et al. Effect of Ashwagandha (Withania somnifera) extract on sleep: A systematic review and meta-analysis. PLoS One. 2021;16(9):e0257843. PubMed: 34559859

2. Langade D, et al. Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Insomnia and Anxiety: A Double-blind, Randomized, Placebo-controlled Study. Cureus. 2019;11(9):e5797. PMC: 6827862

Bioavailability Enhancement Research:

1. Dudhatra GB, et al. A comprehensive review on pharmacotherapeutics of herbal bioenhancers. ScientificWorldJournal. 2012;2012:637953. PMC: 3634921

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Important Disclaimer

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Always consult with your healthcare provider before starting any new supplement regimen, especially if you have pre-existing health conditions or are taking medications.

The research cited represents studies conducted on individual ingredients and may not reflect the specific formulation of this product. Individual results may vary based on sleep hygiene, stress levels, health status, and other factors. The research cited represents potential benefits and does not guarantee specific outcomes for all users.